natural alternatives to isosorbide mononitrate
The https:// ensures that you are connecting to the Do not change the dosing times unless directed by your doctor. Natural Medicines. My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms. Mayo Clinic does not endorse companies or products. I took this for 4 days, and my headaches were unbearable. Bookshelf Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. So get a ct scan brain apart from cardiology workup. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. GoodRx works to make its website accessible to all, including those with disabilities. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. https://naturalmedicines.therapeuticresearch.com. Data were assessed for carryover and time effects. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. https://naturalmedicines.therapeuticresearch.com. B12 and folic acid is essential along with iron. Diabetes treatment: Can cinnamon lower blood sugar? If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice. Eur Heart J. May also be prescribed off label for Esophageal Spasm. Make sure laboratory personnel and all your doctors know you use this drug. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. A very serious allergic reaction to this drug is rare. Upgrade to Patient Pro Medical Professional? Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. Browse all drugs on eHealthMe. Unable to load your collection due to an error, Unable to load your delegates due to an error. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. Isosorbide mononitrate belongs to the group of medicines called nitrates. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). Your doctor may tell you to take a pain reliever to treat your headaches. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This site complies with the HONcode standard for trustworthy health information: verify here. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. Along with its needed effects, a medicine may cause some unwanted effects. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. The IR version can help treat and prevent angina. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. DUMQOL (DUtch Mononitrate Quality of Life) Study Group. Dated August 2017. Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. MeSH Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Mehta D. Herbal & dietary supplements. This medicine is available only with your doctor's prescription. Natural remedies for depression: Are they effective? Accessed Sept. 7, 2022. Other medications may be prescribed by your doctor for these conditions. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. With any medication, there are risks and benefits. Consult your pharmacist or local waste disposal company. Bauer B (expert opinion). "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Isosorbide mononitrate: isosorbide mononitrate. For details see our conditions. In the remainder of them there was a highly significant time effect: the overall numbers of headache attacks in the first period of active treatment versus the second were 2,380 vs 1,400 (P < 0.003). Always consult your healthcare provider. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. Things to remember when you fill your prescription. Copyright 2023 IBM Watson Health. Of the total drug interactions, Take this medication by mouth as directed by your doctor, usually twice a day. It can cause your blood pressure to become dangerously low. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Murray MT. http://www.upandaway.org. This information is aggregated and used to produce personalized reports that patients can reference. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. If it is within 2 hours of the next dose, skip the missed dose. Isosorbide is in a class of medications called vasodilators. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Moderately clinically significant. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Accessed Sept. 7, 2022. Do not stop taking it without consulting your doctor. Methods: In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). 2023 eHealthMe.com. Treatment and prognosis of heart failure with preserved ejection . from the best health experts in the business. health information, we will treat all of that information as protected health Canada residents can call a provincial poison control center. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. There are 195 drugs known to interact with information highlighted below and resubmit the form. WebMD does not provide medical advice, diagnosis or treatment. View interaction reports for isosorbide mononitrate and the medicines listed below. If headaches continue or become severe, tell your doctor promptly. Take isosorbide exactly as directed. This product may contain inactive ingredients, which can cause allergic reactions or other problems. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? If you notice any other effects, check with your healthcare professional. Limit alcoholic beverages. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). This document does not contain all possible drug interactions. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It can make you really dizzy. It might help to keep the room cool and use a fan. (2) One in 3 patients never experienced headache from the given dosages. Ask your pharmacist any questions you have about refilling your prescription. Do not keep out-of-date or unwanted medicines. Take the missed dose as soon as you remember it. Journal of the American College of Cardiology. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Unless there is a specific reason you need the brand, the generic medication will be a better value. St. Joseph 81 mg Aspirin Enteric Safety-Coated. Isosorbide mononitrate helps to prevent angina chest pain from developing. Isosorbide (C6H10O4), also called D-Isosorbide dinitrate, is a bio-product sourced from starch. Seek alternatives to the CYP3A4 substrate when possible. Ask your doctor before using aspirin together with alcohol. Accessed Sept. 7, 2022. Other side effects not listed may also occur in some patients. Isosorbide mononitrate helps to prevent angina chest pain from developing. Careers. Herbal supplements are natural, so they must be safe, right? Isosorbide controls chest pain but does not cure coronary artery disease. In: Textbook of Natural Medicine. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. https://naturalmedicines.therapeuticresearch.com. The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. isosorbide mononitrate, along with The dose is according to the body weight and severity of the condition. Call your doctor if you have any unusual problems while you are taking this medication. Accessed Sept. 7, 2022. . The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. Overview of herbal medicines and dietary supplements. The most common side-effect is headache. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. Isosorbide mononitrate (Monoket) is not a medication you take if you think you are having a heart attack. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Duplication for commercial use must be authorized by ASHP. Selected from data included with permission and copyrighted by First Databank, Inc. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. Herbal supplements can strongly affect the body. If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate. Cleophas TJ, Niemeyer MG, van Der Wall EE. Don't drink alcohol while taking isosorbide mononitrate (Monoket). Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. If you forget to take a dose, take it as soon as you remember. Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. US residents can call their local poison control center at 1-800-222-1222. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonAcid or sour stomachanxietyback painbelchingblemishes on the skinbloatedbreast painburning feeling in the chest or stomachburning, dry, or itching eyeschange in color visionchanges in visioncold sweatscongestionconstipationcontinuing ringing or buzzing or other unexplained noise in the earscough producing mucusdecreased interest in sexual intercoursedifficulty seeing at nightdifficulty with movingdischarge, excessive tearingdouble visiondrooping upper eyelidsdull ache or feeling of pressure or heaviness in the legsearacheexcess air or gas in the stomach or intestinesfeeling of constant movement of self or surroundingsfeeling of warmthfeeling unusually coldfrequent urge to defecatefrozen shoulderfull feelinghearing lossheartburnhyperventilationinability to have or keep an erectionincreased appetiteincreased sensitivity of the eyes to sunlightincreased sputumindigestionirritabilityitching skin near damaged veinslack or loss of strengthloss in sexual ability, desire, drive, or performancemuscle or bone painmuscle stiffness or weaknessnightmaresnoisy breathingpain or tenderness around the eyes and cheekbonespassing gaspimplespoor concentrationrashredness of the face, neck, arms, and occasionally, upper chestredness, pain, swelling of the eye, eyelid, or inner lining of the eyelidredness, swelling, or soreness of the tonguerestlessnessseeing doublesensation of spinningsleepiness or unusual drowsinesssmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscopesmall lumps under the skinsore mouth or tonguestiff neckstomach bloating, burning, cramping, or painstomach discomfort or upsetstraining while passing stoolstuffy nosesudden sweatingswollen feet and anklestender, swollen glands in the necktenderness in the stomach areaterrifying dreams causing sleep disturbancestooth disordertrouble swallowinguncontrolled twisting movements of the neckvoice changesweight losswhite patches in the mouth, tongue, or throatOther side effects not listed may also occur in some patients. May also be prescribed off label for Esophageal Spasm. Consult your doctor before breast-feeding. Tolerance is more likely to happen if you don't take your dose at the same time every day. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). In case of overdose, call the poison control helpline at 1-800-222-1222. All rights reserved. Take your next dose at the regular time. Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". Contact your provider right away if you feel as if you are going to pass out and are experiencing an irregular heartbeat, nausea, vomiting, changes in vision, more sweating, or cold and clammy skin. It does not work fast enough to relieve the pain of an angina attack that has already started. There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. The herb licorice may lower warfarin levels and can add to digoxin's effects. Follow directions about how much medicine to take. Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. AskMayoExpert. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. Are you looking for information on isosorbide dinitrate (Isordil) instead? Isosorbide mononitrate (Monoket) can cause some serious health issues. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). 2005 - 2023 WebMD LLC. 7 disease interactions. Usually avoid combinations; use it only under special circumstances. Egton Medical Information Systems Limited. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . The table below contains some of the most common ones associated with isosorbide mononitrate. Herbal supplements can strongly affect the body. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Longer-acting tablets and capsules are taken once daily in the morning. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). Take them to your local pharmacy which will dispose of them for you. This is called a medicine interaction. Registered in England and Wales. Consult your doctor for more details. If you have any problems with the way your liver works, or any problems with the way your kidneys work. For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). What should I know regarding pregnancy, nursing and administering Isosorbide Mononitrate to children or the elderly? This drug may make you dizzy. privacy practices. All Rights Reserved. Isosorbide may cause other side effects. 41% of reviewers reported a positive effect, while 50% reported a negative effect. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. https://www.uptodate.com/contents/search. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. Some of these medicine interactions can be risky. Do not double the dose to catch up. Methods: Each day, take the first dose when you wake up, then take the second dose 7 hours later. The extended-release capsule usually is taken once daily. Sept. 26, 2022. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. Saper RB. This is not a complete list of possible side effects. Keep this medication in the container it came in, tightly closed, and out of reach of children. Review/update the https://naturalmedicines.therapeuticresearch.com. Does Alcohol Raise Your Blood Pressure? Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Bethesda, MD 20894, Web Policies The information on this page is written and peer reviewed by qualified clinicians. Higher dosages are associated with stomach irritation and Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. What happens if I stop taking isosorbide mononitrate (Monoket)? Advertising revenue supports our not-for-profit mission. We study millions of patients and 5,000 more each day. Keep all medications away from children and pets. [2] If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. But only about 25% of people who take herbal supplements tell their health care providers. Isosorbide mononitrate. If we combine this information with your protected To use the sharing features on this page, please enable JavaScript. FOIA We comply with the HONcode standard for trustworthy health information. This list covers only some interactions. 8600 Rockville Pike Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. All rights reserved. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. Talk to your provider if you notice your chest pain starts to get worse. Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller. It is best not to drink alcohol while you are on isosorbide mononitrate. https://naturalmedicines.therapeuticresearch.com. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Your doctor will probably tell you not to take isosorbide if you are taking one of these medications. Generic alternatives may be available. Ask your pharmacist for a list of the ingredients. Natural Medicines. Headache is often a sign that this medication is working. Cardizem may also be used for purposes not listed in this medication guide. [2] It is taken by mouth. This is a condition where the heart does not beat as efficiently as it should. Unless your doctor tells you otherwise, continue your normal diet. official website and that any information you provide is encrypted Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. https://naturalmedicines.therapeuticresearch.com. You can start a phase IV clinical trial to monitor Isosorbide mononitrate safety and effectiveness. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. Now, youll enjoy a streamlined experience created specifically for healthcare providers. Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. Accessed Sept. 7, 2022. 88 ratings on Drugs.com. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Enter other medications to view a detailed report. 2017; doi:10.1016/j.jacc.2016.11.078. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. All rights reserved. Instead, the best way to dispose of your medication is through a medicine take-back program. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Store it at room temperature and away from excess heat and moisture (not in the bathroom). What are the interactions of Isosorbide Mononitrate ? Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. In Canada - Call your doctor for medical advice about side effects. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Patient does not provide medical advice, diagnosis or treatment. Does Isosorbide Mononitrate interact with other drugs you are taking? It can cause your blood pressure to become dangerously low. This content does not have an English version. Check with your doctor immediately if any of the following side effects occur: burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, irregular, pounding, or racing heartbeat or pulse, itching, pain, redness, or swelling on the leg, numbness or tingling in the hands, feet, or lips, pain or discomfort in the arms, jaw, back, or neck, pain, tension, and weakness upon walking that subsides during periods of rest, shakiness in the legs, arms, hands, or feet, swelling of the face, fingers, feet, or lower legs, trembling or shaking of the hands or feet, vomiting of blood or material that looks like coffee grounds, Bluish-colored lips, fingernails, or palms. Use this medication regularly to get the most benefit from it. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. 2023 Lybrate, Inc. All rights reserved. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
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